:root{
  --font-body:"Roboto", Arial, Helvetica, sans-serif;
  --font-mono:"Roboto Mono", "SFMono-Regular", Consolas, "Liberation Mono", monospace;
  --font-pagination:"DM Sans", "Roboto", Arial, Helvetica, sans-serif;
  --shell-max-width:2400px;
  --dashboard-gap:clamp(10px, 1.4vw, 10px);
  --card-inline-pad:12px;
  --dashboard-left-ratio:.55;
  --hpo-box-edge-inset:6px;
  --control-gap:8px;
  --control-height:28px;
  --control-inline-pad:12px;
  --control-radius:10px;
  --control-font-size:11px;
  --control-font-weight:700;
  --phenotype-divider-top-gap:10px;
  --phenotype-divider-bottom-gap:25px;
  --top-stack-height:clamp(388px, 34vh, 540px);
  --genes-card-height:var(--top-stack-height);
  --variants-card-height:clamp(618px, 56vh, 900px);
  --gnomad-card-height:clamp(184px, 17vh, 260px);
  --predictions-card-height:clamp(618px, 56vh, 900px);
  --bg:#ffffff;
  --card:#ffffff;
  --border:#e8e8eb;
  --border-strong:#e2e2e7;
  --text:#2d2d31;
  --muted:#a1a5ae;
  --muted-2:#777b84;
  --shadow:0 8px 24px rgba(17,24,39,0.04);
  --danger:#ef4f4f;
  --link:#547df8;
  --selected:#dbe8ff;
  --pill:#1d1d1f;
  --blue-soft:#e8f0ff;
  --rose-soft:#ffe8ea;
  --amber-soft:#fff1d8;
}
*{box-sizing:border-box}
html,body{height:100%}
body{
  margin:0;
  background:var(--bg);
  color:var(--text);
  font-family:var(--font-body);
  -webkit-font-smoothing:antialiased;
}
.app-shell{
  max-width:var(--shell-max-width);
  margin:18px auto 24px;
  padding:0 clamp(18px, 2vw, 32px);
}
.topbar{
  position:relative;
  display:grid;
  grid-template-columns: auto 1fr auto;
  align-items:center;
  gap:20px;
  margin-bottom:10px;
}
.brand{
  display:flex;
  align-items:center;
  gap:18px;
  min-width:0;
}
.app-logo{
  display:flex;
  align-items:center;
  gap:2px;
  flex-shrink:0;
  color:inherit;
  text-decoration:none;
}
.app-logo-text{
  font-family:'Zen Dots', cursive;
  font-size:12px;
  font-style:normal;
  font-weight:400;
  line-height:100%;
  color:#000;
}
.app-logo-lab-wrap{
  position:relative;
  width:40px;
  height:12px;
  display:flex;
  align-items:center;
  justify-content:center;
  overflow:visible;
}
.app-logo-ring{
  position:absolute;
  width:40.004px;
  height:38.917px;
  top:50%;
  left:50%;
  transform:translate(-50%,-50%) rotate(15deg);
  transition:transform 0.6s ease-out;
}
.app-logo-ring.spinning{
  animation:logo-spin 1s linear infinite;
}
@keyframes logo-spin{
  from{transform:translate(-50%,-50%) rotate(0deg)}
  to{transform:translate(-50%,-50%) rotate(360deg)}
}
.app-logo-lab{
  position:relative;
  font-family:'Zen Dots', cursive;
  font-size:12px;
  font-style:normal;
  font-weight:400;
  line-height:100%;
  color:#000;
}
.search-wrap{
  width:390px;
  position:relative;
}
.contact-link{
  width:38px;
  height:38px;
  display:inline-flex;
  align-items:center;
  justify-content:center;
  border:1px solid var(--border-strong);
  border-radius:999px;
  background:#fbfbfc;
  color:#4f5560;
  text-decoration:none;
  flex-shrink:0;
  transition:background-color .18s ease, border-color .18s ease, color .18s ease, transform .18s ease;
}
.contact-link:hover{
  background:#f4f5f7;
  border-color:#d7d9df;
  color:#2d3138;
  transform:translateY(-1px);
}
.search-wrap input{
  width:100%;
  height:38px;
  border:1px solid var(--border-strong);
  border-radius:999px;
  background:#fbfbfc;
  padding:0 42px 0 18px;
  font-size:14px;
  color:#5b6068;
  outline:none;
}
.search-wrap input::placeholder{color:#b7bbc3}
.search-icon{
  position:absolute;
  right:15px;
  top:50%;
  transform:translateY(-50%);
  color:#2b2b2c;
  pointer-events:none;
}
.org-logos{
  display:flex;
  align-items:center;
  gap:14px;
  justify-self:end;
  margin-right:var(--hpo-box-edge-inset);
}
.org-logo-bcm{width:48px;height:48px;object-fit:contain;border-radius:4px}
.org-logo-tch{width:auto;height:52px;object-fit:contain}
.center-nav{
  position:absolute;
  top:50%;
  left:calc((100% - var(--dashboard-gap)) * var(--dashboard-left-ratio) + var(--dashboard-gap) + var(--card-inline-pad));
  transform:translateY(-50%);
  display:flex;
  justify-content:flex-start;
  margin:0;
}
.pill-group{
  display:flex;
  gap:var(--control-gap);
}
.pill{
  appearance:none;
  -webkit-appearance:none;
  display:inline-flex;
  align-items:center;
  justify-content:center;
  height:var(--control-height);
  padding:0 var(--control-inline-pad);
  border-radius:var(--control-radius);
  border:1px solid transparent;
  font-size:var(--control-font-size);
  font-weight:var(--control-font-weight);
  line-height:1;
  background:transparent;
  color:#70757d;
  cursor:pointer;
  box-shadow:none;
  transition:background-color .18s ease, border-color .18s ease, color .18s ease;
}
.pill.is-active{
  border-color:#1a1a1b;
  background:#1a1a1b;
  color:#fff;
  box-shadow:var(--shadow);
}

.dashboard{
  display:grid;
  grid-template-columns:minmax(940px, 1.1fr) minmax(760px, .9fr);
  gap:var(--dashboard-gap);
}
.column{
  display:flex;
  flex-direction:column;
  gap:14px;
  min-width:0;
}
.right-top-stack{
  display:flex;
  flex-direction:column;
  gap:8px;
  min-height:var(--top-stack-height);
  height:var(--top-stack-height);
  flex-shrink:0;
}
.card{
  background:var(--card);
  border:1px solid var(--border);
  border-radius:12px;
  box-shadow:var(--shadow);
  overflow:hidden;
}
.card.pad{padding:14px 16px 12px}
.genes-card{
  min-height:var(--genes-card-height);
  height:var(--genes-card-height);
}
.variants-card{
  min-height:var(--variants-card-height);
  height:var(--variants-card-height);
}
.phenotype-card{flex:1;min-height:0}
.gnomad-card{
  min-height:var(--gnomad-card-height);
  height:var(--gnomad-card-height);
  display:flex;
}
.gnomad-card-body{
  display:flex;
  flex:1;
  flex-direction:column;
  padding:12px 14px 10px;
}
.gnomad-card-head{
  display:flex;
  align-items:center;
  justify-content:space-between;
  gap:12px;
}
.gnomad-gene-meta{
  margin:-2px 0 10px;
  display:flex;
  flex-wrap:wrap;
  align-items:flex-start;
  gap:6px;
  color:#7f848d;
  font-size:11px;
  line-height:1.5;
}
.gnomad-summary-text{
  display:inline;
}
.gnomad-gene-meta.is-expanded .gnomad-summary-text{
  display:block;
  max-width:60%;
}
.summary-toggle{
  border:0;
  background:transparent;
  color:#4b73e8;
  font:inherit;
  font-weight:700;
  padding:0;
  cursor:pointer;
}
.summary-toggle:hover{
  text-decoration:underline;
}
.gnomad-table-wrap{
  flex:1;
  overflow:auto;
}
.gnomad-table th,
.gnomad-table td{
  padding:9px 8px;
}
.gnomad-table thead th{
  color:#9ca1aa;
}
.gnomad-table tbody td{
  color:#48505a;
  border-top:1px solid #efeff2;
}
.gnomad-table tbody tr:first-child td{
  border-top:1px solid #efeff2;
}
.family-row{
  display:grid;
  grid-template-columns:1fr 1fr;
  gap:4px;
}
.family-card,.cohort-card{min-height:120px}
.predictions-card{min-height:var(--predictions-card-height);height:var(--predictions-card-height);flex:none}

.table-card{
  display:flex;
  flex-direction:column;
}
.table-inner{
  padding:10px 12px 0;
}
.table-scroll{overflow:auto hidden}
.genes-card .table-inner,
.variants-card .table-inner{
  display:flex;
  flex:1;
  min-height:0;
}
.genes-card .table-scroll,
.variants-card .table-scroll{
  flex:1;
  min-height:0;
  overflow:auto;
  scrollbar-width:thin;
}
.genes-card table,
.variants-card table{
  table-layout:auto;
}
.genes-card thead th,
.variants-card thead th{
  position:sticky;
  top:0;
  background:var(--card);
  z-index:1;
}
table{
  width:100%;
  border-collapse:collapse;
  table-layout:fixed;
}
th,td{
  padding:9px 8px;
  text-align:left;
  vertical-align:middle;
  font-size:11px;
  white-space:nowrap;
  overflow:hidden;
  text-overflow:ellipsis;
}
thead th{
  padding-top:8px;
  padding-bottom:10px;
  color:var(--muted);
  font-size:10px;
  font-weight:700;
  letter-spacing:.03em;
  border-bottom:1px solid #eeeeef;
}
thead th .th-main{
  display:block;
  color:#8f95a0;
  font-size:10px;
  font-weight:700;
  letter-spacing:.03em;
}
thead th .th-sub{
  display:block;
  margin-top:2px;
  color:#c0c4cb;
  font-size:8px;
  font-weight:600;
}
thead th.primary .th-main{
  color:#25272b;
  font-size:12px;
}
.genes-card th:nth-child(7),
.genes-card th:nth-child(8),
.genes-card th:nth-child(9),
.genes-card td:nth-child(7),
.genes-card td:nth-child(8),
.genes-card td:nth-child(9){
  text-align:center;
}
tbody td{
  color:#474b54;
  border-bottom:0;
  transition:background-color .18s ease;
}
tbody tr:hover td{
  background:#fbfbfd;
}
.data-row{
  cursor:pointer;
}
.data-row.is-selected td{
  background:rgba(226,236,255,0.52);
}
.data-row.is-selected:hover td{
  background:rgba(218,230,255,0.68);
}
.data-row.is-selected td:first-child{
  overflow:visible;
  font-weight:400;
}
.cell-selected-wrap{
  position:relative;
  display:inline-block;
  padding:0 4px 4px 0;
  vertical-align:middle;
  transform:translate(0,0);
  transition:transform .2s ease;
}
.cell-selected{
  position:relative;
  display:inline-flex;
  align-items:center;
  justify-content:center;
  width:60px;
  height:22px;
  padding:0;
  border-radius:5px;
  border:1px solid rgba(255,255,255,0.52);
  background:linear-gradient(180deg, rgba(255,255,255,0.48) 0%, rgba(223,236,255,0.28) 100%);
  color:#17191d;
  font-size:12px;
  font-weight:400;
  line-height:1;
  text-decoration:none;
  letter-spacing:.01em;
  white-space:nowrap;
  overflow:hidden;
  text-overflow:ellipsis;
  box-shadow:
    inset 0 1px 0 rgba(255,255,255,0.7),
    0 10px 22px rgba(88,122,188,0.14);
  backdrop-filter:blur(14px);
  -webkit-backdrop-filter:blur(14px);
  z-index:1;
}
.cell-selected-bg{
  position:absolute;
  top:4px;
  left:4px;
  width:60px;
  height:22px;
  border-radius:5px;
  background:linear-gradient(90deg, #1142a5 0%, #bad1fb 100%);
  box-shadow:0 10px 20px rgba(66,104,180,0.24);
  pointer-events:none;
  z-index:0;
}
.data-row.is-selected:hover .cell-selected-wrap{
  transform:translate(-1px,-1px);
}
.gene-link{
  color:#30353d;
  text-decoration:none;
  font-weight:700;
}
.effect-danger{color:var(--danger)}
.link{
  color:var(--link);
  text-decoration:none;
}
.mono{
  font-family:var(--font-mono);
  font-size:10px;
}
.card-footer{
  margin-top:auto;
  display:flex;
  justify-content:space-between;
  align-items:center;
  padding:10px 12px 14px;
  color:#8b9098;
  font-size:12px;
}
.footer-meta{
  display:flex;
  align-items:center;
  gap:10px;
  min-width:0;
}
.scroll-controls{
  display:flex;
  align-items:center;
  gap:4px;
}
.scroll-controls.is-hidden{
  visibility:hidden;
  pointer-events:none;
}
.scroll-btn{
  width:22px;
  height:22px;
  border:1px solid var(--border-strong);
  background:#fff;
  color:#70757d;
  border-radius:999px;
  cursor:pointer;
  font-size:11px;
  line-height:1;
  padding:0;
}
.scroll-btn:disabled{
  opacity:.35;
  cursor:default;
}
.pagination{
  display:flex;
  align-items:center;
  gap:10px;
  user-select:none;
}
.page-btn{
  border:0;
  background:transparent;
  color:#70757d;
  font-size:14px;
  padding:0 2px;
  cursor:pointer;
}
.page-num{
  font-family:var(--font-pagination);
  display:inline-block;
  font-size:11px;
  color:#5c616a;
  cursor:pointer;
  padding:0 2px;
  background:transparent;
  border:0;
  border-radius:0;
  appearance:none;
  -webkit-appearance:none;
  box-shadow:none;
}
.page-num.active{
  min-width:20px;
  height:20px;
  display:inline-flex;
  align-items:center;
  justify-content:center;
  border-radius:999px;
  background:#000;
  color:#fff;
  padding:0;
}
.ellipsis{
  color:#888d95;
  font-size:12px;
}

.icon-carousel-wrap{
  display:flex;
  align-items:center;
  gap:6px;
  min-width:0;
  margin:0 0 4px 6px;
}
.carousel-nav{
  width:18px;
  height:18px;
  border:0;
  background:transparent;
  color:#8a8f97;
  border-radius:50%;
  cursor:pointer;
  font-size:14px;
  line-height:1;
  display:none;
}
.carousel-window{
  overflow:hidden;
  width:170px;
}
.carousel-track{
  display:flex;
  gap:8px;
  transition:transform .25s ease;
}
.icon-chip{
  width:32px;
  height:32px;
  flex:0 0 32px;
  border-radius:999px;
  border:0;
  background:transparent;
  padding:0;
  cursor:pointer;
  display:grid;
  place-items:center;
  opacity:.8;
}
.icon-chip img{
  width:30px;
  height:30px;
  display:block;
}
.icon-chip.active{
  opacity:1;
  transform:translateY(0);
}
.icon-chip:not(.active) img{
  filter:grayscale(100%) brightness(1.05);
}
.hpo-logo{
  display:block;
  width:auto;
  height:32px;
  margin:0 0 4px 6px;
  opacity:.95;
  flex-shrink:0;
  align-self:flex-start;
}
.phenotype-body{
  display:grid;
  grid-template-columns: 1.08fr 1px .92fr;
  grid-template-rows:minmax(0,1fr);
  margin-top:8px;
  height:200px;
}
.phenotype-body::before{
  content:'';
  grid-column:2;
  grid-row:1;
  background:#eeeeef;
  align-self:start;
  height:calc(100% - var(--phenotype-divider-top-gap) - var(--phenotype-divider-bottom-gap));
  margin-top:var(--phenotype-divider-top-gap);
  border-radius:1px;
}
.phenotype-half{
  padding:0 12px var(--phenotype-divider-bottom-gap);
  display:flex;
  flex-direction:column;
  min-height:0;
  overflow:hidden;
}
.phenotype-half > .mini-table,
.phenotype-half > .icon-carousel-wrap,
.phenotype-half > .hpo-logo{
  flex-shrink:0;
}
.phenotype-scroll{
  flex:1 1 auto;
  overflow-y:auto;
  min-height:0;
  max-height:130px;
}
.phenotype-table{
  width:100%;
}
.phenotype-table thead th{
  position:sticky;
  top:0;
  z-index:1;
  background:var(--card);
}
.hpo-half .phenotype-table thead th{
  background:#f4f5f7;
}
/* Selected OMIM phenotype row */
.omim-row{
  cursor:pointer;
  border-radius:6px;
  transition:background .15s;
}
.omim-row:hover{
  background:#f4f5f7;
}
.omim-row.is-selected{
  background:#f4f5f7;
}
.omim-row.is-selected td:first-child{
  font-weight:600;
}
/* HPO shaded container */
.phenotype-half.hpo-half{
  margin:4px var(--hpo-box-edge-inset) var(--phenotype-divider-bottom-gap);
  padding:0;
}
.hpo-table-shell{
  display:flex;
  flex:1 1 auto;
  flex-direction:column;
  background:#f4f5f7;
  border-radius:8px;
  padding:6px 12px 10px;
  overflow:hidden;
  min-height:0;
}
.mini-table{
  width:100%;
}
.mini-table th,.mini-table td{
  padding:8px 6px;
  font-size:11px;
}
.mini-table th{
  color:#989ca4;
  font-size:10px;
  font-weight:700;
  border-bottom:0;
}
.mini-table thead th{
  padding-bottom:8px;
}
.mini-table tbody td{
  border-bottom:0;
}
.split-card{
  padding:10px 14px;
}
.card-title,
th.section-title{
  color:#232428;
  font-size:12px;
  font-weight:700;
  margin-bottom:10px;
}
.gnomad-card-head .card-title{
  margin-bottom:0;
}
.marrvel-logo{
  display:block;
  height:16px;
  width:auto;
  object-fit:contain;
  flex-shrink:0;
}
.marrvel-link{
  display:inline-flex;
  align-items:center;
  text-decoration:none;
}
.compact-table th,.compact-table td{
  padding:6px 6px;
}
.compact-table th{
  color:#b0b4bc;
  font-size:9px;
}
.badge{
  display:inline-flex;
  align-items:center;
  height:18px;
  padding:0 7px;
  border-radius:999px;
  font-size:9px;
  font-weight:700;
}
.badge.rose{background:var(--rose-soft);color:#f26b6b}
.badge.amber{background:var(--amber-soft);color:#c89a2d}
.badge.blue{background:var(--blue-soft);color:#6b92ff}
.badge.indigo{background:#dfe9ff;color:#456ed6}
.badge.slate{background:#eef1f4;color:#68717d}

.predictions-wrap{
  display:flex;
  flex-direction:column;
  height:100%;
  min-height:0;
}
.predictions-head{
  padding:14px 14px 8px;
  flex-shrink:0;
}
.prediction-grid{
  display:grid;
  grid-template-columns:1fr 1fr;
  gap:6px;
}
.prediction-grid.is-hidden{
  display:none;
}
.metric-card{
  min-height:58px;
  border:1px solid #efeff2;
  border-radius:4px;
  padding:6px 8px;
  background:#fff;
}
.metric-group-label{
  grid-column:1 / -1;
  margin:4px 0 -1px;
  color:#b0b4bc;
  font-size:9px;
  font-weight:700;
  text-transform:uppercase;
}
.metric-label{
  color:#b0b4bc;
  font-size:9px;
  font-weight:700;
  line-height:1.2;
}
.metric-value{
  margin-top:3px;
  font-size:12px;
  color:#434851;
  overflow-wrap:anywhere;
}
.metric-value.danger{color:var(--danger);font-weight:700}
.prediction-detail{
  flex:1;
  min-height:0;
  margin:12px 14px 0;
  border-top:1px solid #efeff2;
  color:#7f848d;
  font-size:12px;
  padding:18px 4px 10px;
  overflow:auto;
}
.prediction-detail.is-standalone{
  margin-top:0;
  border-top:0;
  padding-top:12px;
}
.prediction-detail h4,
.prediction-detail .tab-headline{
  margin:0 0 10px;
  color:#33363c;
  font-size:13px;
}
.prediction-detail p{
  max-width:720px;
  line-height:1.5;
  margin:0;
}
.tab-list{
  display:flex;
  gap:var(--control-gap);
  border-top:1px solid #efeff2;
  padding:14px 14px 16px;
  flex-shrink:0;
}
.tab-btn{
  font-family:var(--font-pagination);
  appearance:none;
  -webkit-appearance:none;
  display:inline-flex;
  align-items:center;
  justify-content:center;
  flex:0 0 auto;
  min-height:var(--control-height);
  padding:0 var(--control-inline-pad);
  border-radius:var(--control-radius);
  border:1px solid transparent;
  background:transparent;
  color:#70757d;
  font-size:var(--control-font-size);
  font-weight:var(--control-font-weight);
  line-height:1;
  cursor:pointer;
  box-shadow:none;
  transition:background-color .18s ease, border-color .18s ease, color .18s ease;
}
.tab-btn.active{
  border-color:#1a1a1b;
  background:#1a1a1b;
  color:#fff;
  box-shadow:var(--shadow);
}
.bullets{
  margin:0;
  padding-left:18px;
  line-height:1.7;
}
.inheritance-layout{
  display:grid;
  grid-template-columns:minmax(0, 1fr) minmax(0, .92fr);
  gap:22px;
}
.inheritance-panel{
  padding:0;
  border:0;
  background:transparent;
}
.inheritance-panel-cohort{
  border-left:1px solid #efeff2;
  padding-left:22px;
}
.inheritance-section-head{
  display:flex;
  align-items:center;
  gap:8px;
  margin-bottom:16px;
}
.inheritance-section-icon{
  display:inline-flex;
  align-items:center;
  justify-content:center;
  color:#2962ff;
}
.inheritance-note{
  margin:0 0 16px;
  color:#7f848d;
  font-size:11px;
  line-height:1.5;
}
.inheritance-family-stack{
  display:flex;
  flex-direction:column;
  gap:14px;
}
.inheritance-phenotype-summary{
  border:1px solid #ebedf1;
  border-radius:12px;
  background:#f8fafc;
  padding:14px 16px;
  margin-bottom:14px;
}
.inheritance-phenotype-title{
  color:#1f2430;
  font-size:11px;
  font-weight:700;
  margin-bottom:6px;
}
.inheritance-phenotype-summary p{
  margin:0;
  color:#5d6572;
  font-size:12px;
  line-height:1.55;
}
.inheritance-member-card{
  border:1px solid #ebedf1;
  border-radius:14px;
  background:#fff;
  padding:18px;
  box-shadow:0 10px 24px rgba(17,24,39,0.04);
}
.inheritance-member-card.is-featured{
  background:#f3f7fb;
  border-color:#dfe8f3;
}
.inheritance-member-top{
  display:flex;
  align-items:center;
  justify-content:space-between;
  gap:14px;
  margin-bottom:14px;
}
.inheritance-member-ident{
  display:flex;
  align-items:center;
  gap:12px;
  min-width:0;
}
.inheritance-member-badges{
  display:flex;
  align-items:center;
  flex-wrap:wrap;
  justify-content:flex-end;
  gap:6px;
}
.inheritance-member-icon{
  width:38px;
  height:38px;
  border-radius:12px;
  background:#e8f0fb;
  color:#5b87dd;
  display:flex;
  align-items:center;
  justify-content:center;
  flex-shrink:0;
}
.inheritance-member-name{
  color:#1f2430;
  font-size:13px;
  font-weight:700;
}
.inheritance-member-sample{
  margin-top:3px;
  color:#7b818a;
  font-size:11px;
}
.inheritance-genotype-grid{
  display:grid;
  grid-template-columns:repeat(4, minmax(0, 1fr));
  gap:10px;
  padding:14px 16px;
  border-radius:10px;
  background:#f8fafc;
}
.inheritance-genotype-stat{
  min-width:0;
}
.inheritance-genotype-label{
  color:#8e96a2;
  font-size:9px;
  font-weight:700;
  letter-spacing:.08em;
}
.inheritance-genotype-value{
  margin-top:4px;
  color:#1f2430;
  font-size:12px;
  font-weight:700;
}
.inheritance-cohort-callout{
  border-left:3px solid #2962ff;
  background:#f4f7ff;
  border-radius:8px;
  padding:14px 16px;
  margin-bottom:16px;
}
.inheritance-cohort-callout-line{
  color:#3a4250;
  font-size:12px;
  line-height:1.55;
}
.inheritance-cohort-callout-line + .inheritance-cohort-callout-line{
  margin-top:4px;
}
.inheritance-cohort-summary{
  display:grid;
  grid-template-columns:1.2fr .7fr .7fr;
  gap:10px;
  margin-bottom:16px;
}
.inheritance-cohort-metric{
  border:1px solid #ebedf1;
  border-radius:12px;
  background:#fff;
  padding:12px 14px;
}
.inheritance-cohort-label{
  color:#98a0ab;
  font-size:9px;
  font-weight:700;
  letter-spacing:.08em;
}
.inheritance-cohort-value{
  margin-top:4px;
  color:#1f2430;
  font-size:12px;
  font-weight:700;
  word-break:break-word;
}
.inheritance-sample-card{
  border:1px solid #ebedf1;
  border-radius:14px;
  background:#fff;
  padding:16px;
}
.inheritance-sample-card-title{
  color:#333842;
  font-size:12px;
  font-weight:700;
  margin-bottom:12px;
}
.inheritance-sample-list{
  display:flex;
  flex-wrap:wrap;
  gap:10px;
}
.inheritance-sample-chip{
  display:inline-flex;
  align-items:center;
  min-height:28px;
  padding:0 10px;
  border-radius:999px;
  background:#f4f5f7;
  color:#4a5160;
  font-size:11px;
  font-weight:700;
}
.inheritance-empty{
  color:#8b919b;
  font-size:11px;
  line-height:1.5;
}

@media (max-width: 1280px){
  .topbar{position:static}
  .center-nav{
    position:static;
    top:auto;
    left:auto;
    transform:none;
    justify-content:center;
    margin:6px 0 8px;
  }
  .dashboard{grid-template-columns:1fr}
  .search-wrap{width:100%;max-width:420px}
  .inheritance-layout{grid-template-columns:1fr}
  .inheritance-panel-cohort{border-left:0;padding-left:0}
  .inheritance-genotype-grid{grid-template-columns:repeat(2, minmax(0, 1fr))}
  .inheritance-cohort-summary{grid-template-columns:1fr}
}

@media (min-width: 1680px){
  th,td{
    padding:10px 10px;
  }
  .genes-card .table-inner,
  .variants-card .table-inner{
    padding:12px 14px 0;
  }
  .card-footer{
    padding:12px 14px 16px;
  }
  .phenotype-body{
    height:100%;
  }
  .phenotype-scroll{
    max-height:none;
  }
}

.igv-panel{
  display:flex;
  flex-direction:column;
  gap:10px;
}
.igv-toolbar{
  display:grid;
  grid-template-columns:minmax(280px, 1fr) auto;
  gap:10px;
  align-items:end;
}
.igv-toolbar-secondary{
  grid-template-columns:repeat(2, minmax(220px, 1fr)) auto;
}
.igv-field{
  display:flex;
  flex-direction:column;
  gap:5px;
}
.igv-field label{
  font-size:11px;
  letter-spacing:.03em;
  font-weight:700;
  color:#6a7080;
  text-transform:uppercase;
}
.igv-field input{
  height:34px;
  border:1px solid var(--border-strong);
  border-radius:8px;
  padding:0 10px;
  font:500 12px/1 var(--font-body);
  color:#374151;
  background:#fff;
}
.tab-action-btn{
  height:34px;
  border-radius:8px;
  border:1px solid #1f2937;
  background:#111827;
  color:#fff;
  font-size:12px;
  font-weight:700;
  padding:0 12px;
  cursor:pointer;
}
.igv-status{
  margin:0;
  font-size:12px;
  color:#46617e;
}
.igv-help{
  margin:0;
  font-size:11px;
  color:#7a8291;
}
.igv-status.error{
  color:var(--danger);
}
.igv-browser-host{
  min-height:340px;
  border:1px solid var(--border);
  border-radius:10px;
  overflow:hidden;
  background:#fff;
}